GR-OPENSCREEN offers researchers from Greece and around the world open access to a uniquely broad range of high technologies and tools for the systematic screening of chemical substances for their biological effects. GR-OPENSCREEN integrates high-capacity screening platforms throughout GReece, which jointly use a rationally selected compound collection, comprising up to 60.000 commercial and proprietary compounds collected from chemists.

GR-OPENSCREEN will collaboratively develop novel molecular tool compounds with external users from various disciplines of the life sciences. GR-OPENSCREEN has no bias towards target families, biological topics or models. GR-OPENSCREEN explicitly advocates wide-ranging projects that will enhance cross-fertilization between disciplines.

GR-OPENSCREEN supports all stages of a tool development project, including assay adaptation, high-throughput screening, and chemical optimisation of the ‘hit’ compounds. All generated tool compounds and data will be made available in an open access database.